District of Columbia Intellectual and Developmental Disabilities Research Center
About Us
The District of Columbia Intellectual and Developmental Disabilities Research Center (DC-IDDRC) conducts multidisciplinary, basic, translational, clinical and community research in intellectual and developmental disabilities (IDDs). Our mission is to expand the understanding of the causes underlying IDDs, develop innovative therapies, and prevent or attenuate the full effects of these disorders, so that each child can achieve her/his full physical and intellectual potential.
Children’s National Hospital (lead institution) has played a crucial role in bringing together four major academic institutions in D.C. – Children’s National, the George Washington University, Georgetown University and Howard University – to create, grow and sustain a vigorous center and a supportive environment for IDD investigators.
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Major Themes
Neural development and neurodevelopmental disorders
Fetal and neonatal brain injury
Genetic disorders
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Contact
Nikkie Adesida Senior Research Center Manager nadesida@childensnational.org
Featured Publications
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Association of prenatal maternal anxiety with fetal regional brain connectivity
De Asis-Cruz J, Krishnamurthy D, Zhao L, Kapse K, Vezina G, Andescavage N, Quistorff J, Lopez C, Limperopoulos C. JAMA Network Open 7;3(12):e2022349 DOI:10.1001/jamanetworkopen.2020.22349 December (2020) -
Age and sex influences gamma-aminobutyric acid concentrations in the developing brain of very premature infants
Basu SK, Pradhan S, Jacobs MB, Said M, Kapse K, Murnick J, Whitehead M, Chang T, du Plessis A, Limperopoulos C. Scientific Reports 10(1):10549 DOI:10.1038/s41598-020-67188-y June (2020) -
Functional brain connectivity in ex utero premature infants compared to in utero fetuses
De Asis-Cruz J, Kapse K, Basu SK, Said M, Scheinost D, Murnick J, Chang T, du Plessis A, Limperopoulos C. Neuroimage 219:117043 DOI:10.1016/j.neuroimage.2020.117043 June (2020) -
Non-invasive measurement of biochemical profiles in the healthy fetal brain
Pradhan S, Kapse K, Jacobs M, Niforatos Andescavage N, Quistorff JL, Lopez C, Bannatine KL, Reinholdt Andersen N, Vezina G, Limperopoulos C. Neuroimage 219:117016 DOI:10.1016/j.neuroimage.2020.117016 June (2020) -
Improved brain growth and microstructural development in breast milk-fed very low birth weight premature infants
Ottolini KM, Andescavage N, Kapse K, Jacobs M, Limperopoulos C. Acta Paediatrica DOI: 10.1111/apa.15168 January (2020)