Hahn Laboratory
About the Lab
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Lab Focus Areas
Cystic Fibrosis
Antimicrobial Pharmacokinetics
Airway Microbiome
Antibiotic Resistance -
Partnerships
George Washington University Milken Institute School of Public Health
Computational Biology Institute at George Washington University -
Contact
Andrea Hahn, M.D., M.S. Principal Investigator alhahn@childrensnational.org 202-476-3340
Featured Publications
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Airway microbial diversity is decreased in young children with cystic fibrosis compared to healthy controls but improved with CFTR modulation
Hahn A, Burrell A, Ansusinha E, Peng D, Chaney H, Sami I, Perez GF, Koumbourlis AC, McCarter R, Freishtat RJ, Crandall KA, Zemanick ET PubMed PMID: 32514485; PubMed Central PMCID: PMC7267737. Heliyon 6(6):e04104. doi: 10.1016/j.heliyon.2020.e04104. eCollection June (2020) -
Longitudinal associations of the cystic fibrosis airway microbiome and volatile metabolites: A case study
Hahn A, Whiteson K, Davis TJ, Phan J, Sami I, Koumbourlis AC, Freishtat RJ, Crandall KA, Bean HD PubMed PMID: 32411616; PubMed Central PMCID: PMC7198769. Front Cell Infect Microbiol 10:174. doi: 10.3389/fcimb.2020.00174. eCollection (2020) -
Changes in microbiome diversity following beta-lactam antibiotic treatment are associated with therapeutic versus subtherapeutic antibiotic exposure in cystic fibrosis
Hahn A, Fanous H, Jensen C, Chaney H, Sami I, Perez GF, Koumbourlis AC, Louie S, Bost JE, van den Anker JN, Freishtat RJ, Zemanick ET, Crandall KA PubMed PMID: 30796252; PubMed Central PMCID: PMC6385179. Sci Rep 9(1):2534. doi: 10.1038/s41598-019-38984-y February (2019) -
Antibiotic multidrug resistance in the cystic fibrosis airway microbiome is associated with decreased diversity
Hahn A, Burrell A, Fanous H, Chaney H, Sami I, Perez GF, Koumbourlis AC, Freishtat RJ, Crandall KA PubMed PMID: 30238064; PubMed Central PMCID: PMC6143701. Heliyon 4(9):e00795. doi: 10.1016/j.heliyon.2018.e00795. eCollection September (2018) -
Relationship of pulmonary outcomes, microbiology, and serum antibiotic concentrations in cystic fibrosis patients
Hahn A, Jensen C, Fanous H, Chaney H, Sami I, Perez GF, Louie S, Koumbourlis AC, Bost JE, van den Anker JN PubMed PMID: 30429692; PubMed Central PMCID: PMC6213626. J Pediatr Pharmacol Ther 23(5):379-389. doi: 10.5863/1551-6776-23.5.379 September-October (2018)