Morizono Laboratory

Featured Publications

• Criticality: A new concept of severity of illness for hospitalized children

  Rivera EAT, Patel AK, Chamberlain JM, Workman TE, Heneghan JA, Redd D, Morizono H, Kim D, Bost JE, Pollack MM PMID: 32932406 Pediatr Crit Care Med doi: 10.1097/PCC.0000000000002560 September (2020)

• A mutation-independent CRISPR-Cas9-mediated gene targeting approach to treat a murine model of ornithine transcarbamylase deficiency

  Wang L, Yang Y, Breton C, Bell P, Li M, Zhang J, Che Y, Saveliev A, He Z, White J, Latshaw C, Xu C, McMenamin D, Yu H, Morizono H, Batshaw ML, Wilson JM PMID: 32095520 Sci Adv 6(7):eaax5701. doi: 10.1126/sciadv.aax5701. eCollection February (2020)

• Baseline human gut microbiota profile in healthy people and standard reporting template

  King CH, Desai H, Sylvetsky AC, LoTempio J, Ayanyan S, Carrie J, Crandall KA, Fochtman BC, Gasparyan L, Gulzar N, Howell P, Issa N, Krampis K, Mishra L, Morizono H, Pisegna JR, Rao S, Ren Y, Simonyan V, Smith K, VedBrat S, Yao MD, Mazumder R PMID: 31509535 PLoS One 14(9):e0206484. doi: 10.1371/journal.pone.0206484. eCollection September (2019)

• Disease-causing mutations in the promoter and enhancer of the ornithine transcarbamylase gene

  Jang YJ, LaBella AL, Feeney TP, Braverman N, Tuchman M, Morizono H, Ah Mew N, Caldovic L PMID: 29282796 Hum Mutat 39(4):527-536. doi: 10.1002/humu.23394. Epub April (2018)

• Enabling precision medicine via standard communication of HTS provenance, analysis, and results

  Alterovitz G, Dean D, Goble C, Crusoe MR, Soiland-Reyes S, Bell A, Hayes A, Suresh A, Purkayastha A, King CH, Taylor D, Johanson E, Thompson EE, Donaldson E, Morizono H, Tsang H, Vora JK, Goecks J, Yao J, Almeida JS, Keeney J, Addepalli K, Krampis K, Smith KM, Guo L, Walderhaug M, Schito M, Ezewudo M, Guimera N, Walsh P, Kahsay R, Gottipati S, Rodwell TC, Bloom T, Lai Y, Simonyan V, Mazumder R PMID: 30596645 PLoS Biol 16(12):e3000099. doi: 10.1371/journal.pbio.3000099. eCollection December (2018)