Publications

Featured Publications

• TGF-beta-driven muscle degeneration and failed regeneration underlie disease onset in DMD mouse model

  Mázala DA, Novak JS, Hogarth MW, Nearing M, Adusumalli P, Tully CB, Habib NF, Gordish-Dressman H, Chen YW, Jaiswal JK, Partridge TA JCI Insight 5(6): e135703. doi: 10.1172/jci.insight.135703 (2020)

• Mitochondrial fragmentation enables localized signaling required for cell repair

  Horn A, Raavicharla S, Shah S, Cox D, Jaiswal JK J Cell Biology 219(5):e201909154. doi: 10.1083/jcb.201909154 (2020)

• Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B

  Hogarth MW, Defour A, Lazarski C, Gallardo E, Diaz Manera J, Partridge TA, Nagaraju K, Jaiswal JK Nature Communications 10(1):2430. doi: 10.1038/s41467-019-10438-z (2019)

• Membrane stabilization by modified steroid offers a potential therapy for muscular dystrophy due to dysferlin deficit

  Sreetama SC, Chandra G, Van der Meulen JH, Ahmad MM, Suzuki P, Bhuvanendran S, Nagaraju K, Hoffman EP, Jaiswal JK Molecular Therapy 26(9):2231-2242. doi: 10.1016/j.ymthe.2018.07.021 September (2018)

• Mitochondria mediate cell membrane repair and contribute to Duchenne muscular dystrophy

  Vila MC, Rayavarapu S, Hogarth MW, Van der Meulen JH, Horn A, Defour A, Takeda S, Brown KJ, Hathout Y, Nagaraju K, and Jaiswal JK PMCID: PMC5299714 Cell Death and Differentiation 24:330-342 (2017)

• Mitochondrial redox signaling enables repair of injured skeletal muscle cells

  Horn A, Van der Meulen JH, Defour A, Hogarth M, Sreetama SC, Reed A, Scheffer L, Chandel NS, Jaiswal JK Science Signaling 10(495):eaaj1978. doi: 10.1126/scisignal.aaj1978 (2017)

• Myoblasts and macrophages are required for therapeutic morpholino antisense oligonucleotide delivery to dystrophic muscle

  Novak JS, Hogarth MW, Boehler JF, Nearing M, Vila MC, Heredia R, Fiorillo AA, Zhang A, Hathout Y, Hoffman EP, Jaiswal JK, Nagaraju K, Cirak S, Partridge TA Nature Communications 8(1):941 October (2017)

• Mechanism of Ca²⁺-triggered ESCRT assembly and regulation of cell membrane repair

  Scheffer LL, Sreetama SC, Sharma N, Medikayala S, Brown KJ, Defour A, Jaiswal JK Nature Communications 5:5646. doi: 10.1038/ncomms6646 (2014)

• S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells

  Jaiswal JK, Lauritzen SP, Scheffer L, Sakaguchi M, Bunkenborg J, Simon SM, Kallunki T, Jaattela M and Nylandsted J PMC4026250 Nature Communications 5:3795 (2014)

• Exocytosis of post-Golgi vesicles is regulated by components of the endocytic machinery

  Jaiswal JK, Rivera VM, Simon SM Cell 137(7):1308-19. doi: 10.1016/j.cell.2009.04.064 (2009)

• Imaging single events at the cell membrane

  Jaiswal JK and Simon, SM Nature Chemical Biology 3, 92-98 (2007)

• Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy

  Voura, EB, Jaiswal JK, Mattoussi H, and Simon, SM Nature Medicine 10, 993-998 (2004)

• Use of quantum dots for cellular imaging

  Jaiswal, JK, Goldman ER, Mattoussi H, and Simon SM Nature Methods 1, 73-78 (2004)

• Long-term multiple color imaging of live cells using quantum dot bioconjugates

  Jaiswal, JK, Mattoussi, H, Mauro, JM, and Simon, SM Nature Biotechnology 21, 47-51 (2003)

• Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells

  Jaiswal JK, Andrews NW, Simon SM J Cell Biology 159(4):625-35. doi: 10.1083/jcb.200208154. Epub (2002)