Haydar Lab

Publications

Featured Publications

  • Longitudinal neuroanatomical and behavioral analyses show phenotypic drift and variability in the Ts65Dn mouse model of Down syndrome

    Shaw, P.R., Klein, J.A., Aziz, N.M. and Haydar T.F. Dis. Model. Mech dmm.046243. doi:10.1242/dmm.046243. August (2020)

  • Neurogenesis, myelination, and circuitry: The case for a distributed therapeutic regimen in Down syndrome

    Haydar, T.F. Am. J. Intellect. Dev. Disabil 125(2):100-102. (2020)

  • Lessons from single cell sequencing in CNS cell specification and function

    Li, Z., Tyler, W.A. and Haydar, T.F Curr. Opin. Genet. Dev 65:138-143 July (2020)

  • Transcriptional priming as a conserved mechanism of lineage diversification in the developing mouse and human neocortex

    Li, Z*., Tyler, W.A.,* Zeldich, E., Santpere Baro, G., Okamoto, M., Gao, T., Li, M., Sestan, N.† and Haydar T.F. Sci. Adv 6(45):eabd2068. doi: 10.1126/sciadv.abd2068 (2020)

  • Distinct neocortical progenitor lineages fine-tune neuronal diversity in a layer-specific manner

    Guillamon-Vivancos, T., Tyler, W.A., Medalla, M., Chang, W.W., Okamoto, M., Haydar, T.F.* and Luebke, J.I. Cerebral Cortex 29(3):1121-1138 March (2019)

  • Spatiotemporal development of spinal neuronal and glial populations in the Ts65Dn mouse model of Down syndrome

    Aziz, N.M., Klein, J.A., Brady, M.R., Olmos-Serrano, J.L., Gallo, V. and Haydar, T.F J. Neurodev. Disord. 11(1): 35. doi: 10.1186/s11689-019-9294-9. December (2019)

  • Lifespan analysis of brain development, gene expression and behavioral phenotypes in the Ts1Cje, Ts65Dn and Dp(16)1/Yey mouse models of Down syndrome

    Aziz, N.M., Guedj, F. Pennings, J.L.A., Olmos-Serrano, J.L., Seigel A., Haydar, T.F.* and Bianchi, D.W. Dis Model Mech 11(6) pii: dmm031013. doi: 10.1242/dmm.031013 (2018)

  • CLASP2 links Reelin to the cytoskeleton during neocortical development

    Dillon, G.M.*, Tyler, W.A.*, Omuro, K.C., Kambouris, J., Tyminski, C., Henry, S., Haydar, T.F., Beffert, U., Ho, A Neuron 93(6): 1344-135 (2017)

  • Down syndrome developmental brain transcriptome reveals defective oligodendrocyte differentiation and myelination

    Olmos-Serrano, J.L.1, Kang, H.J.1, Tyler, W.A.1, Cheng, F.1, Zhu, Y., Silbereis, J.C., Pletikos, M., Jankovic-Rapan, L., Cramer, N.P., Galdzicki, Z., Goodliffe, J., Peters, A., Sethares, C., Haydar, T.F.* and Sestan, N. Neuron 89: 1-15 (2016)

  • Longitudinal measures of cognition in the Ts65Dn mouse: Refining windows and defining modalities for therapeutic intervention in Down syndrome

    Olmos-Serrano, J.L., Tyler, W.A, Cabral, H.J. and Haydar, T.F. Exp. Neurol 279:40-56. (2016)

  • Absence of prenatal forebrain defects in the Dp(16)1Yey/+ mouse model of Down syndrome

    Goodliffe, J.W., Olmos-Serrano, J.L., Aziz, N.M., Pennings, J.L., Guedj, F., Bianchi, D.W. and Haydar, T.F. Journal of Neuroscience 36(10):2926-44 (2016)

  • Neural precursor lineages specify distinct neocortical pyramidal neuron types

    Tyler, WA, Medalla, M., Guillamon-Vivancos, T., Luebke, J.I. and Haydar, T.F. Journal of Neuroscience 35(15):6142-52 (2015)